Polypropylene provides the best inert surface that prevents DNA, RNA, and enzymes from binding while improving recovery from wells even when working with minute volumes. Polycarbonate provides mechanical stability, and it facilitates handling of the plates. The enhanced stiffness offers improved plane parallelism in the plate deck before, during, and after a PCR, and it ensures a more secure seal. Bending or curving of the skirt is virtually eliminated; making twin.tec PCR plates the ideal choice for use with automation or robotics (skirted and semi-skirted formats).

Eppendorf twin.tec PCR plates also offer a 20% reduction in wall thickness compared to standard thin-walled tubes. This provides a snug fit for the well against thermal blocks, and it ensures virtually undisturbed heat transfer from the block to the sample. Raised well rims optimize sealing effectiveness and reduce the risk of cross-contamination. All commonly used sealing methods—cap strips, adhesive films, and foils—can be applied to Eppendorf twin.tec PCR plates for heat sealing and ultimate protection against evaporation.